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Updated: Jun 26, 2026

Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis
Published on: October 13, 2023
Imaging of endometrial pathology
Barton F Lane1, Jade J Wong-You-Cheong
1Department of Diagnostic Radiology, University of Maryland School of Medicine, Baltimore, Maryland, USA. blane@umm.edu
Understanding normal endometrial imaging is key to diagnosing gynecologic conditions. This review covers imaging of the normal and abnormal endometrium, including ultrasound, MRI, and other modalities, to aid accurate diagnosis.
Area of Science:
- Radiology
- Gynecologic Imaging
- Endometrial Pathology
Background:
- The endometrium undergoes cyclical changes during the menstrual cycle and atrophies post-menopause.
- Accurate interpretation of endometrial imaging requires knowledge of the normal spectrum of appearances.
- Distinguishing normal variations from pathology is crucial for patient management.
Purpose of the Study:
- To review the imaging features of the normal and abnormal endometrium.
- To discuss conditions that can mimic endometrial pathology.
- To emphasize the primary role of ultrasound and MRI in endometrial evaluation.
Main Methods:
- Review of imaging modalities including ultrasound with sonohysterography and magnetic resonance imaging (MRI).
- Discussion of the complementary roles of hysterosalpingography, computed tomography (CT), and 18-fluorodeoxyglucose-positron emission tomography (FDG-PET).
- Focus on characteristic imaging findings for normal and abnormal endometrial states.
Main Results:
- Detailed description of normal endometrial appearances across different phases of the menstrual cycle and post-menopause.
- Identification of key imaging features distinguishing benign conditions from malignant endometrial pathology.
- Highlighting imaging findings of entities that can mimic endometrial disease.
Conclusions:
- Familiarity with normal endometrial imaging is essential for accurate diagnosis.
- Ultrasound with sonohysterography and MRI are the preferred modalities for endometrial assessment.
- A comprehensive understanding of imaging findings aids in the detection and management of endometrial conditions.
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