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Oral formulations of budesonide: a novel treatment for inflammatory bowel disease
R Paul Svoboda1, Dhaval H Patel, Kevin W Olden
1Division of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.
Abstract:
Budesonide is a promising drug for a variety of documented applications and has potential in gastroenterology. Its unique local mechanism of delivery and efficient first-pass metabolism, resulting in fewer systemic adverse effects than with conventional glucocorticoids, makes this a desirable drug for clinical practice. This drug has shown promise in treating a wide spectrum of inflammatory diseases from inflammatory bowel disease and other colitides to autoimmune liver diseases. Future research should focus on ways to increase delivery methods to promote long-term usage for maintenance therapy for the disease entities listed above, as well as for other potential nongastrointestinal conditions.
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