Rapid response to a case of mumps: implications for preventing transmission at a medical research facility

Gabriela Salmón-Mulanovich1, Gregory Utz, Andrés G Lescano

  • 1Naval Medical Research Center Detachment, Peru.

Salud Publica De Mexico
|January 31, 2009
PubMed
Abstract

Insights

Rapid response to a mumps outbreak in Peru prevented secondary cases. Prompt investigation and vaccination of healthcare workers protected both staff and non-human primates from mumps transmission.

Area of Science:

  • Occupational Health
  • Infectious Disease Epidemiology
  • Veterinary Public Health

Background:

  • A mumps outbreak occurred in a laboratory technician at a U.S. Naval Medical Research Center in Peru.
  • The potential for transmission to staff and the non-human primate (NHP) colony necessitated immediate intervention.

Observation:

  • 81% of 106 staff members had close contact with the infected individual.
  • Only 7% of exposed staff had received the MMR vaccine, and 18% of potentially susceptible individuals lacked immunity.
  • No secondary human cases were reported, and NHP colony access was restricted.

Findings:

  • A swift occupational health response, including interviews and IgG testing, identified susceptible individuals.
  • All identified susceptible staff were vaccinated with the MMR vaccine.
  • The implemented measures successfully prevented further mumps transmission within the facility.

Implications:

  • Demonstrates the critical importance of rapid and comprehensive occupational health strategies in controlling infectious disease outbreaks in research settings.
  • Highlights the need for robust vaccination policies and surveillance to protect both human and animal populations in high-risk environments.
  • Emphasizes the successful containment of mumps, safeguarding both personnel and valuable research animals.

Related Concept Videos

Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis: