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Updated: Jun 26, 2026
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Operating Procedures of the Electrochemotherapy for Treatment of Tumor in Dogs and Cats
Published on: October 24, 2016
Electrochemotherapy-induced radiation recall in a cat
Enrico P Spugnini1, Ivan Dotsinsky, Nikolay Mudrov
1S.A.F.U. Department, Regina Elena Cancer Institute, Rome, Italy. info@enricospugnini.net
In Vivo (Athens, Greece)
|February 3, 2009
Summary
Electrochemotherapy effectively treated a cat's recurring fibrosarcoma. However, caution is advised when using electrochemotherapy (ECT) in previously irradiated areas due to potential radiation recall side effects.
Area of Science:
- Veterinary Medicine
- Oncology
- Biomedical Engineering
Background:
- Electrochemotherapy (ECT) is an emerging, cost-effective cancer treatment for companion animals.
- This study investigates ECT's application for a recurring fibrosarcoma in a feline patient.
Observation:
- A cat with a recurring fibrosarcoma was treated using cisplatin delivered via biphasic electrical pulses.
- The tumor showed no recurrence over a five-month follow-up period.
- The cat developed severe erythema, moist desquamation, and ulceration at the previous irradiation site.
Findings:
- Successful tumor ablation was achieved with electrochemotherapy.
- The adverse effects observed were consistent with radiation recall syndrome.
- This suggests electrochemotherapy should be used cautiously in previously irradiated tissues.
Implications:
- Electrochemotherapy shows promise as a salvage therapy for relapsing tumors in veterinary oncology.
- Further research is needed to understand and mitigate risks associated with ECT in previously irradiated sites.
- This case highlights the importance of considering prior treatment history when planning electrochemotherapy.
