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Related Experiment Video

Updated: Jun 26, 2026

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

Enucleation for open globe injury.

Aaron Savar¹, Michael T Andreoli, Carolyn E Kloek

¹Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.

American Journal of Ophthalmology

|February 3, 2009

Summary

This summary is machine-generated.

Most open globe injuries can be repaired without enucleation. Secondary enucleation is typically for blind, painful eyes, but observation is an option for those with no light perception.

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Area of Science:

Ophthalmology
Trauma Surgery

Background:

Open globe injuries are a significant cause of vision loss.
Enucleation is a surgical procedure to remove the eye.

Observation:

A retrospective study reviewed 660 open globe injuries over seven years.
55 patients (8.3%) underwent enucleation (11 primary, 44 secondary).
Ruptures were more likely to require enucleation than lacerations.

Findings:

The primary indication for secondary enucleation was a blind, painful eye.
Only two patients (0.3%) developed sympathetic ophthalmia and retained good vision.
Most open globe injuries can be managed without enucleation.

Implications:

Surgical repair is often successful for open globe injuries.
Patient choice and quality of life are key considerations for enucleation.
Close observation is a viable option for eyes with no light perception.