Kikuchi-Fujimoto syndrome presenting to a sexual health clinic

We report on a 37-year-old woman who presented with a six-week history of bilateral, tender lymph nodes in her groin. An initial biopsy was done with the histology 'suggestive of lymphogranuloma venereum (LGV)'. She had not had sexual intercourse for over two years and had no symptoms or signs of note to report. Examination revealed large, smooth tender lymph nodes above the inguinal ligament bilaterally with no other areas of lymphadenopathy. Due to a possible diagnosis of LGV, three weeks of doxycycline was given. A further review of the histology slides revealed 'subacute necrotizing lymphadenitis' highly suggestive of Kikuchi-Fujimoto syndrome of unknown cause, which is usually self-limiting. Subsequent follow-up of the patient revealed a reduction in the lymph nodes size with little tenderness.