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Use of third-generation cephalosporins. Streptococci
1Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, North Carolina.
Abstract:
The third-generation cephalosporins are highly active against nonenterococcal streptococci. The subgroup of ceftizoxime, ceftriaxone, and cefotaxime are similar to penicillin in their activities by weight; and the drug with the longest half-life, ceftriaxone, offers the potential for home therapy for selected patients with endocarditis.