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Updated: Jun 26, 2026

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
Large mycotic pseudoaneurysm of the left circumflex treated with antibiotics and covered stent
Nasir Shariff1, William Combs, Justin Roberts
1Department of Medicine, Lehigh Valley Hospital, 1240 S. Cedar Crest Blvd., Allentown, PA 18103, USA. nasirshariff@gmail.com
Abstract:
Coronary artery mycotic aneurysms are rare complications of infective endocarditis. They are usually managed surgically with excision of the aneurysm. This surgical procedure has high morbidity and mortality. We report a case of a giant mycotic coronary aneurysm following infective endocarditis which was treated with intravenous antibiotics and covered stent. This case highlights a new treatment modality in critically ill patients.
Insights
Giant mycotic coronary aneurysms, rare complications of infective endocarditis, can be treated with antibiotics and covered stents. This approach offers a less invasive option for critically ill patients, potentially reducing surgical risks.
Area of Science:
- Cardiology
- Infectious Diseases
- Vascular Surgery
Background:
- Mycotic aneurysms of the coronary arteries are uncommon but serious complications of infective endocarditis.
- Traditional management involves surgical excision, carrying significant risks of morbidity and mortality.
Observation:
- A case of a giant mycotic coronary aneurysm secondary to infective endocarditis is presented.
- The patient was critically ill, making conventional surgical intervention a high-risk option.
Findings:
- The patient was successfully treated with a combination of intravenous antibiotics and a novel covered stent placement.
- This minimally invasive approach effectively managed the giant mycotic coronary aneurysm.
Implications:
- This case suggests that endovascular repair with covered stents may be a viable alternative to surgery for select patients with mycotic coronary aneurysms.
- This treatment modality could improve outcomes for critically ill patients with this rare condition, reducing the need for high-risk open-heart surgery.
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