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Related Experiment Video

Updated: Jun 26, 2026

A Liposome Membrane Permeability Assay for Investigating the Effects of Phosphatidylinositol Phosphate Groups on Membranotropic Action of Venom PLA2
10:31

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Published on: September 26, 2025

Anti phospholipid syndrome.

M T Miah1, M A Hoque, S R Sutradhar

  • 1Department of Medicine, Mymensingh Medical College Hospital, Mymensingh, Bangladesh. titum21@ yahoo.com

Mymensingh Medical Journal : MMJ
|February 3, 2009
PubMed
Summary
This summary is machine-generated.

Anti Phospholipid Syndrome (APS) can cause serious vascular events, including stroke, in young adults. Early diagnosis and anticoagulation treatment are crucial for managing APS complications and improving patient outcomes.

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Area of Science:

  • Neurology
  • Rheumatology
  • Obstetrics

Background:

  • Anti Phospholipid Syndrome (APS) is a condition characterized by recurrent thrombosis and/or pregnancy complications.
  • APS can be primary or secondary to other autoimmune diseases.
  • Clinical manifestations primarily result from vascular thrombosis and embolism.

Observation:

  • A 34-year-old female presented with acute neurological deficits (lateral medullary syndrome) and a chronic leg ulcer.
  • She had a history of recurrent pregnancy loss.
  • Despite normal cardiovascular risk factors, investigations confirmed APS.

Findings:

  • The patient's neurological symptoms were attributed to stroke secondary to APS.
  • No underlying secondary cause for APS was identified.
  • The patient fulfilled the diagnostic criteria for APS.

Implications:

  • This case highlights the importance of considering APS in young patients with unexplained stroke, particularly with a history of pregnancy complications.
  • Early diagnosis and management with anticoagulation can lead to favorable outcomes.
  • Raising awareness of APS among clinicians is essential for timely intervention.