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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...

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Related Experiment Video

Updated: Jun 26, 2026

Modeling Mitochondrial Disease Using Brain Organoids: A Focus on Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes
08:56

Modeling Mitochondrial Disease Using Brain Organoids: A Focus on Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes

Published on: October 10, 2025

Kikuchi-Fujimoto disease.

R Parveen1, S H Rahman, R Yasmin

  • 1Dhaka Medical College, and Department of Immunology & Molecular Biology, National Institute of Cancer Research & Hospital, Dhaka, Bangladesh.

Mymensingh Medical Journal : MMJ
|February 3, 2009
PubMed
Summary
This summary is machine-generated.

Kikuchi-Fujimoto disease, a rare condition causing swollen lymph nodes, was diagnosed in a teen after initial tests were inconclusive. Prompt diagnosis and symptomatic treatment led to a full recovery, highlighting the importance of recognizing this benign illness.

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Multimodality Diagnosis of Mesenteric Ischemia
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Multimodality Diagnosis of Mesenteric Ischemia

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Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Area of Science:

  • Immunology
  • Pathology
  • Rare Diseases

Background:

  • Kikuchi-Fujimoto disease (KFD) is a rare, benign, and enigmatic condition of unknown etiology.
  • It often presents with cervical lymphadenopathy, fever, and constitutional symptoms.
  • KFD can mimic other serious conditions like lymphoma, tuberculosis, and autoimmune diseases.

Purpose of the Study:

  • To report a case of Kikuchi-Fujimoto disease in a young Bangladeshi female.
  • To emphasize the diagnostic challenges and the importance of histopathological examination.
  • To highlight the need for clinician and pathologist awareness to prevent misdiagnosis.

Main Methods:

  • Clinical presentation and laboratory investigations of a 14-year-old girl.
  • Initial fine needle aspiration and cytology (FNAC) of cervical lymph nodes.
  • Histopathological examination of an excised lymph node for definitive diagnosis.

Main Results:

  • The patient presented with fever, cervical lymphadenopathy, anorexia, weight loss, and night sweats.
  • Initial investigations for sepsis and autoimmune diseases were negative.
  • FNAC suggested tubercular lymphadenitis, but the patient did not respond to anti-tubercular treatment.
  • Histopathology confirmed Kikuchi-Fujimoto disease, leading to complete recovery with symptomatic treatment.

Conclusions:

  • Kikuchi-Fujimoto disease is a rare, self-limited condition with an excellent prognosis.
  • Accurate diagnosis is crucial to avoid misdiagnosis and inappropriate treatment for conditions like lymphoma or tuberculosis.
  • Increased awareness among clinicians and pathologists can improve patient outcomes.