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Skin and bones. I.

S J Orlow1, K L Watsky, J L Bolognia

  • 1Department of Dermatology, New York University School of Medicine, New York.

Journal of the American Academy of Dermatology
|August 1, 1991
PubMed
Summary

This review covers skin disorders with associated bony changes detectable by radiographs. It categorizes these conditions, with Part I focusing on inherited and congenital diseases impacting bone and calcification.

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Area of Science:

  • Radiology
  • Dermatology
  • Genetics

Background:

  • Skin disorders can manifest with skeletal abnormalities detectable via radiography.
  • Understanding these associations aids in diagnosis and management.
  • Bony changes or calcification abnormalities are key radiographic findings.

Purpose of the Study:

  • To review skin disorders associated with radiographic bony changes or calcification abnormalities.
  • To categorize these disorders for clarity and diagnostic aid.
  • Part I focuses on inherited and congenital conditions.

Main Methods:

  • Literature review of skin disorders with radiographic bone findings.
  • Classification into eight categories based on etiology.
  • Detailed discussion of inherited and congenital categories in Part I.

Main Results:

  • Identified eight categories of skin disorders with associated bony changes.
  • Inherited diseases (e.g., alkaptonuria, neurofibromatosis) are discussed.
  • Congenital disorders (e.g., Sturge-Weber, Proteus syndromes) are detailed.

Conclusions:

  • Radiographs are valuable in diagnosing certain skin disorders by revealing bone abnormalities.
  • Categorization aids in understanding the diverse origins of these conditions.
  • Part I provides a foundation for understanding inherited and congenital types.

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