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Published on: January 19, 2014
Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: statutory challenge
J Brenner1, M Bellaiche, E Gross
1Department of Virology, Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel. yakovb@moag.gov.il
Abstract:
The ultimate goal of a vaccine is to protect vaccinated animals against re-exposure to the same pathogen and provide sterile immunity. However, a cutaneous clinical manifestation appeared, following re-exposure of cattle that had been vaccinated with the RM65 strain, to LSDV infection during an epidemic in 2006-2007. Four thousand six hundred and seven vaccinated cows entered the study after being re-exposed to LSDV infection. Of them, 513 (11%) presented lumps, and there was a marked difference between the proportions of dairy and feedlot animals that were affected: 146 out of 3517 and 367 out of 1090 (6.6 and 33.7%, respectively). This data suggests that the potency of the vaccine need to be re-assessed for beef cattle.
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