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Updated: Jun 26, 2026

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
Published on: July 26, 2022
Neuropathic orofacial pain in children and adolescents
Andres Pinto1, Ramesh Balasubramaniam, Maria Arava-Parastatidis
1Oral Medicine Clinical Center, The Children's Hospital of Philadelphia, Philadelphia, Pa, USA. apinto@dental.upenn.edu
Abstract:
The field of orofacial pain is broad and includes pain conditions affecting the head, face, neck, and intraoral structures. Much has been written about orofacial pain, specifically chronic pain conditions affecting adults. Little is known, however, about the presentation of orofacial pain in pediatric patients. The objective of this paper was to increase awareness and provide information regarding neuropathic orofacial pain in children and adolescents, as pediatric dentists may be asked to participate in the treatment of these patients. Moreover, an accurate history and examination can lead to on early diagnosis of the pain condition, thus avoiding unnecessary or inappropriate dental procedures.
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