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Related Concept Videos

Ultrasonography01:17

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...
X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

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Related Experiment Video

Updated: Jun 26, 2026

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue
07:48

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue

Published on: September 30, 2022

Recent trends in soft-tissue infection imaging.

Nicholas Petruzzi1, Nylla Shanthly, Mathew Thakur

  • 1Department of Radiology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Seminars in Nuclear Medicine
|February 4, 2009
PubMed
Summary

Developing infection-specific imaging agents is crucial for accurately detecting and localizing infections. Techniques like (18)F-FDG-PET offer advantages for imaging various infections, including respiratory and abdominal cases.

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Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice
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Last Updated: Jun 26, 2026

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Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice
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3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography
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3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

Published on: October 24, 2019

Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Radiopharmaceuticals

Background:

  • Current imaging agents localize to infection and inflammation but lack specificity.
  • Occult infections pose diagnostic challenges, necessitating improved imaging techniques.
  • Existing methods for specific infections like inflammatory bowel disease and postoperative spine infections have limitations.

Purpose of the Study:

  • To review current techniques and future directions in infection imaging.
  • To highlight the advantages of (18)F-FDG-PET in infection detection.
  • To discuss the need for infection-specific imaging agents.

Main Methods:

  • Review of current literature on infection imaging techniques.
  • Discussion of radiopharmaceuticals used in scintigraphy and positron emission tomography (PET).
  • Analysis of imaging applications in respiratory, central nervous system, abdominal, and postoperative infections.

Main Results:

  • (18)F-FDG-PET offers superior spatial resolution and does not rely on immune system function, making it advantageous.
  • Quantitative delineation of lung inflammation is an important advancement for monitoring therapeutic response.
  • (99m)Tc-ciprofloxacin SPECT shows high sensitivity for postoperative spine infections, with FDG-PET also showing promise.

Conclusions:

  • Development of infection-specific imaging agents would significantly advance the detection, localization, and quantification of infections.
  • PET/CT is gaining support for imaging patients with fever of unknown origin or compromised immune systems.
  • SPECT/CT and PET/CT imaging of infection-specific agents will enhance clinical reliability in infection localization.