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Updated: Jun 26, 2026

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
Published on: April 28, 2026
Endoscopic resection of early esophageal and gastric neoplasias
Juergen Pohl1, Oliver Pech, Andrea May
1Department of Gastroenterology, Dr. Horst Schmidt Klinik, Medical School of the University of Mainz, Wiesbaden, Germany. pohljuergen@web.de
Abstract:
The advent of endoscopic resection (ER) techniques has enabled gastroenterologists to remove premalignant or neoplastic lesions throughout the gastrointestinal tract. This review discusses the indications and the several techniques of ER in early carcinomas of the esophagus and stomach. Before ER is performed an accurate evaluation of patients and careful staging of lesions is mandatory. After ER of the neoplasia histological assessment of the entire specimen with detailed histological analysis of layer infiltration is crucial. First long-term follow-up studies of large numbers of patients confirm the excellent effectiveness of ER for well-differentiated mucosal lesions without lymphangitic invasions.
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