Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Breslow Thickness and Microsatellite Detection in Primary Cutaneous Melanoma: Implications for Oncologic Surgeons and Patients.

The American surgeon·2026
Same author

Tumor-infiltrating lymphocyte therapy in metastatic vulvar melanoma: A case report and review of the literature.

Gynecologic oncology reports·2026
Same author

A longitudinal, multi-omic atlas reveals the emergence of a spatially organized immunosuppressive ecosystem in resistant melanoma.

Cell reports. Medicine·2026
Same author

Longitudinal ctDNA Monitoring for Postsurgical Disease Surveillance in Patients with Stage I to IIIB Melanoma.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026
Same author

Subgroup analyses of the phase 3 FOCUS study of melphalan/hepatic delivery system in patients with unresectable metastatic uveal melanoma.

Journal of cancer research and clinical oncology·2025
Same author

Gene Expression Profile-Based Test to Predict Melanoma Sentinel Node Status: The MERLIN_001 Study.

JAMA surgery·2025
Same journal

Clinical Impact and Outcomes of Neoadjuvant Systemic Therapy for Invasive Lobular Carcinoma.

Annals of surgical oncology·2026
Same journal

ASO Author Reflections: The Hidden Cost of Gastric Preservation During Cytoreductive Surgery for Pseudomyxoma Peritonei: Understanding the Functional Consequences of Extensive Perigastric Cytoreduction.

Annals of surgical oncology·2026
Same journal

Survival of Squamous Cell Carcinoma Versus Adenocarcinoma in Resected Stage I-III Non-small Cell Lung Cancer.

Annals of surgical oncology·2026
Same journal

ASO Visual Abstract: Quality, Reliability, and Viewer Engagement of YouTube Videos on Esophageal Cancer: A Cross-Sectional Study.

Annals of surgical oncology·2026
Same journal

ASO Visual Abstract: Implementing Paradigm-Shifting Clinical Trials: Real-World Outcomes of Neoadjuvant Versus Adjuvant Immune Checkpoint Inhibitors in Advanced Melanoma Patients.

Annals of surgical oncology·2026
Same journal

Trends in Breast and Axillary Operations in Young Patients with Operable Breast Cancer from the National Cancer Database (NCDB): De-escalation of Axillary Surgery and Increased Use of Radiation.

Annals of surgical oncology·2026
See all related articles

Related Experiment Video

Updated: Jun 25, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
09:38

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

Published on: January 31, 2025

Optimizing regional therapy for melanoma

Georgia M Beasley, Douglas S Tyler

    Annals of Surgical Oncology
    |February 4, 2009
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    A 3D Organotypic Melanoma Spheroid Skin Model
    08:49

    A 3D Organotypic Melanoma Spheroid Skin Model

    Published on: May 18, 2018

    Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
    09:52

    Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma

    Published on: January 25, 2015

    Related Experiment Videos

    Last Updated: Jun 25, 2026

    Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
    09:38

    Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

    Published on: January 31, 2025

    A 3D Organotypic Melanoma Spheroid Skin Model
    08:49

    A 3D Organotypic Melanoma Spheroid Skin Model

    Published on: May 18, 2018

    Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
    09:52

    Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma

    Published on: January 25, 2015