Related Experiment Video
Updated: Jun 25, 2026

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
Published on: May 16, 2019
[Zinc intoxication in a Yorkshire Terrier due to Euro cent ingestion]
1Klinik und Poliklinik für kleine Haustiere, Fachbereich Veterinärmedizin, Freie Universität Berlin, Deutschland. kohn@vetmed.fu-berlin.de
Abstract:
A 5-year old, intact male Yorkshire Terrier was presented due to lethargy, vomiting and diarrhea. Clinical signs included shock, icterus and a painful abdomen. Laboratory examination revealed a severe intravascular hemolytic anemia, a thrombocytopenia and a leukocytosis. The radiographic examination revealed the presence of metallic foreign bodies in the stomach and in the intestine. After stabilisation of the patient with crystalloids, packed red blood cells, ranitidine, metamizole, amoxicilline/clavulanic acid and marbofloxacine, surgery was performed and 5 coins (10 cent, 5 cent, 2 cent) were removed via esophagus and via enterotomy. In the course of disease the dog developed acute renal failure and pancreatitis. The zinc concentration in the serum was 2200 microg/dl, which was 30 times higher compared to a healthy control dog. After 21 days the dog was discharged from the hospital. On day 28 all laboratory values were within the reference range.
Related Concept Videos
Toxicity Testing in Animals
Toxoplasmosis
Rocky Mountain Spotted Fever
Teratogenicity

