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Updated: Jun 25, 2026

Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
Published on: February 21, 2011
[Structural changes in tracheal epithelium in environmental smoke exposed rats--experimental studies]
Anna Biczysko-Murawa1, Janina Stopa, Andrzej Marszałek
1Klinika Stomatologii Zachowawczej i Periodontologii, Katedra Stomatologii Zachowawczej i Periodontologii, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu. abiczysk@op.pl
Abstract:
It has been already proved in many experimental studies that tobacco smoke has multiple toxic effects on respiratory tract cells. Alterations in cilliary epithelium of rats trachea after short exposition to high tobacco smoke concentrations in inhaled air were been determined in current study. Morphological evaluation revealed in lining epithelium decrease in number of cilliary cells and increase in number of goblet cells. The mucous membrane was thickened and infiltrated with inflammatory cells.
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