Related Experiment Video
Updated: Jun 25, 2026
State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Bone speed of sound curves of twin and singleton neonates
Tugba Gursoy1, Murat Yurdakok, Mutlu Hayran
1Neonatal Intensive Care Unit, Zeynep Kamil Maternity and Children's Hospital, Istanbul, Turkey. tugbagursoy@gmail.com
Aim:
To evaluate associations between prenatal risk factors, neonatal characteristics and bone development.
Methods:
Tibial speed of sound (SOS) of 317 neonates whose gestational ages ranged between 25 and 41 weeks and birth weight between 580 and 4,350 g was measured using quantitative ultrasound.
Results:
Bone SOS values correlated significantly with gestational age and birth weight. Small for gestational age (SGA) infants had higher bone SOS values than appropriate for gestational age (AGA) infants. Infants born to multiple pregnancies had lower SOS values than singleton infants so two separate bone SOS curves were made: for singleton infants born AGA (n = 152), and for infants of multiple pregnancies born AGA (n = 104). Infants of preeclamptic mothers had significantly higher SOS values than the infants of mothers without preeclampsia.
Conclusion:
This is the first study reporting bone SOS values of Turkish neonates. Prenatal risk factors, such as preeclampsia, multiple pregnancy, and being SGA, affect the bone development of the fetus.
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