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CD Spectroscopy to Study DNA-Protein Interactions
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Circular dichroism and conformational polymorphism of DNA

Jaroslav Kypr1, Iva Kejnovská, Daniel Renciuk

  • 1Institute of Biophysics, vvi Academy of Sciences of the Czech Republic, Brno, Czech Republic. kypr@ibp.cz

Nucleic Acids Research
|February 5, 2009
PubMed
Summary

Circular dichroic (CD) spectroscopy is a sensitive and versatile method for studying DNA structures. This review highlights its crucial role in understanding various DNA conformations, from B-family to quadruplexes.

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