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Related Experiment Video

Updated: Jun 25, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Multiple primary cranial Ewing's sarcoma in adulthood: case report.

Shinsuke Sato1, Tetsuryu Mitsuyama, Akira Ishii

  • 1Department of Neurosurgery, Tokyo Women's Medical University, Yachiyo Medical Center, Chiba, Japan.

Neurosurgery
|February 5, 2009
PubMed
Summary

Ewing's sarcoma, a rare bone cancer, can manifest as multiple cranial masses in adults. Early diagnosis and treatment, including surgery and radiation, led to a favorable outcome in this case.

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Area of Science:

  • Oncology
  • Neurosurgery
  • Radiology

Background:

  • Ewing's sarcoma typically affects long bones in young individuals.
  • It shares histological and molecular similarities with primitive neuroectodermal tumors.
  • Adult cranial presentation is exceptionally rare.

Observation:

  • A 25-year-old man presented with cranial swelling due to two mass lesions.
  • Imaging revealed osteolytic changes and heterogeneous enhancement in the parietal and frontal regions.
  • Ga-67 citrate scintigraphy confirmed localized cranial uptake.

Findings:

  • Histopathology showed small round cells with rosette formation, consistent with Ewing's sarcoma.
  • Surgical excision of one lesion followed by cranial irradiation and chemotherapy.

Related Experiment Videos

Last Updated: Jun 25, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

  • Complete resolution of the frontal lesion and no recurrence at 1-year follow-up.

    • Implications:

    • Ewing's sarcoma should be considered in the differential diagnosis of adult cranial masses.
    • Multimodality treatment can be effective for cranial Ewing's sarcoma.
    • Further research into adult cranial presentations of this rare tumor is warranted.