Incidental findings during functional magnetic resonance imaging: ethical and procedural issues
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Updated: Jun 25, 2026

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Published on: December 5, 2014
Samuel R Pierce1, Richard T Lauer, Laura A Prosser
1Research Department, Shriners Hospitals for Children in Philadelphia, Philadelphia, Pennsylvania 19140, USA.
Abstract:
Incidental findings during fMRI: ethical and procedural issues.This purpose of this report was to describe the discovery of an incidental finding during functional magnetic resonance imaging in a child of typical development. During the completion of a functional magnetic resonance imaging protocol, an abnormality was noted by a board-certified neuroradiologist that was identified as a benign developmental arachnoid pouch. Significant ethical concerns were apparent with the discovery of an incidental finding, which included how to address the likelihood of incidental findings in the consent and assent process, how to disclose the incidental findings to the subject's parents and primary care provider, and how to minimize subject and parental anxiety.
Insights
Functional magnetic resonance imaging (fMRI) can reveal unexpected incidental findings, like a benign arachnoid pouch in a child. This highlights ethical considerations for informed consent, disclosure, and managing patient anxiety.
Area of Science:
- Neuroimaging
- Pediatric Radiology
- Medical Ethics
Background:
- Functional magnetic resonance imaging (fMRI) is a neuroimaging technique used to assess brain activity.
- Incidental findings are abnormalities discovered unexpectedly during medical imaging for other purposes.
- Ethical guidelines for incidental findings in pediatric neuroimaging are complex and evolving.
Observation:
- A benign developmental arachnoid pouch was incidentally discovered in a typically developing child during an fMRI scan.
- The finding was identified by a board-certified neuroradiologist.
- This case underscores the potential for unexpected discoveries in pediatric neuroimaging.
Findings:
- The discovery of incidental findings during fMRI raises significant ethical and procedural challenges.
- Key issues include informed consent and assent processes, disclosure protocols, and managing patient and parental anxiety.
- Establishing clear guidelines for handling incidental findings is crucial for ethical pediatric neuroimaging.
Implications:
- This case highlights the need for robust ethical frameworks and clear communication strategies in pediatric neuroimaging.
- Radiologists and clinicians must be prepared to address incidental findings sensitively and effectively.
- Future research should focus on developing standardized protocols for managing incidental findings in pediatric populations.
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