Incidental findings during functional magnetic resonance imaging: ethical and procedural issues

Samuel R Pierce1, Richard T Lauer, Laura A Prosser

  • 1Research Department, Shriners Hospitals for Children in Philadelphia, Philadelphia, Pennsylvania 19140, USA.

Insights

Functional magnetic resonance imaging (fMRI) can reveal unexpected incidental findings, like a benign arachnoid pouch in a child. This highlights ethical considerations for informed consent, disclosure, and managing patient anxiety.

Area of Science:

  • Neuroimaging
  • Pediatric Radiology
  • Medical Ethics

Background:

  • Functional magnetic resonance imaging (fMRI) is a neuroimaging technique used to assess brain activity.
  • Incidental findings are abnormalities discovered unexpectedly during medical imaging for other purposes.
  • Ethical guidelines for incidental findings in pediatric neuroimaging are complex and evolving.

Observation:

  • A benign developmental arachnoid pouch was incidentally discovered in a typically developing child during an fMRI scan.
  • The finding was identified by a board-certified neuroradiologist.
  • This case underscores the potential for unexpected discoveries in pediatric neuroimaging.

Findings:

  • The discovery of incidental findings during fMRI raises significant ethical and procedural challenges.
  • Key issues include informed consent and assent processes, disclosure protocols, and managing patient and parental anxiety.
  • Establishing clear guidelines for handling incidental findings is crucial for ethical pediatric neuroimaging.

Implications:

  • This case highlights the need for robust ethical frameworks and clear communication strategies in pediatric neuroimaging.
  • Radiologists and clinicians must be prepared to address incidental findings sensitively and effectively.
  • Future research should focus on developing standardized protocols for managing incidental findings in pediatric populations.