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Updated: Jun 25, 2026

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging
Published on: April 11, 2025
Neuropsychological functioning following complicated vs. uncomplicated mild traumatic brain injury
Rael T Lange1, Grant L Iverson, Michael D Franzen
1British Columbia Mental Health & Addiction Services, 601 West Broadway Street, Vancouver, BC, Canada. rlange@bcmhs.bc.ca
Objective:
It would be logical to assume that patients with intracranial abnormalities (i.e. complicated MTBIs) would have worse outcome than patients without these abnormalities (i.e. uncomplicated MTBIs). However, the literature is limited and somewhat mixed regarding outcome in patients with complicated mild TBIs. The purpose of this study is to employ a carefully controlled research design to compare the acute neuropsychological functioning of patients following complicated and uncomplicated MTBI.
Method:
Participants were 20 patients with complicated MTBI and 20 patients with uncomplicated MTBI selected from an archival database of 465 patients. Patients were carefully matched on age, education, gender, ethnicity, days assessed post-injury and mechanism of injury. Patients were assessed an average of 3.5 days (SD = 1.9) post-injury with 13 common cognitive variables.
Results:
There were significant group differences on only three of the 13 cognitive measures (complicated mild TBI worse than uncomplicated mild TBI). There were no significant differences in the proportion of impaired scores between groups on all measures, with the exception of Hopkins Verbal Learning Test Delayed Recall.
Conclusion:
Patients with complicated MTBIs performed more poorly only on a small number of tests during the acute recovery period.
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