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Related Concept Videos

Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
Classification of Illness01:17

Classification of Illness

The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...
Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...

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Related Experiment Video

Updated: Jun 25, 2026

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
11:05

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

Published on: February 6, 2021

Late recovery from post-traumatic vegetative state.

Elisa Sancisi1, Alberto Battistini, Cristina Di Stefano

  • 1Department of Neurological Sciences, University of Bologna, via Ugo Foscolo, Bologna, Italy. elisa.sancisi@unibo.it

Brain Injury
|February 5, 2009
PubMed
Summary
This summary is machine-generated.

Late recovery of consciousness from a vegetative state is possible, even after 19 months. This case study shows a patient achieving moderate disability and independent living after severe traumatic brain injury.

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Last Updated: Jun 25, 2026

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
11:05

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Published on: February 6, 2021

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats
10:51

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Published on: May 11, 2018

Assessment and Communication for People with Disorders of Consciousness
07:37

Assessment and Communication for People with Disorders of Consciousness

Published on: August 1, 2017

Area of Science:

  • Neuroscience
  • Neurology
  • Traumatic Brain Injury

Background:

  • Late recovery of consciousness after 12 months in a vegetative state is rare and typically results in severe disability.
  • The prognosis for patients in a vegetative state for extended periods is generally poor.

Observation:

  • A 22-year-old male experienced a traumatic brain injury in December 2000, leading to a vegetative state.
  • Consciousness recovery occurred 19 months post-injury, followed by a 7-year period of slow motor and cognitive functional improvement.

Findings:

  • The patient achieved a moderate disability level, enabling independent community living.
  • Functional recovery included independent ambulation, speech, daily living activities, and resumption of university studies and part-time employment.

Implications:

  • This case challenges the notion that prolonged vegetative states preclude significant functional recovery.
  • Long-term rehabilitation programs and interventions like cranioplasty may play a role in unexpected late recoveries.
  • Highlights the potential for continued neuroplasticity and functional improvement years after severe brain injury.