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Related Experiment Videos

Auditory brainstem response during systemic hyperthermia.

H Takahashi1, R Tanaka, Y Sekihara

  • 1Department of Neurosurgery, Niigata University, Japan.

International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
|July 1, 1991
PubMed
Summary

Brain temperature significantly impacts auditory brainstem response (ABR) latency during induced hyperthermia. Shorter ABR latency indicates elevated brain temperature, offering a potential clinical monitoring tool.

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Area of Science:

  • Neuroscience
  • Physiology
  • Medical Technology

Background:

  • Systemic hyperthermia can affect neurological function.
  • Monitoring brain temperature is crucial during certain medical procedures.

Purpose of the Study:

  • To investigate the relationship between brain temperature and auditory brainstem response (ABR) latency.
  • To evaluate the potential of ABR as a clinical index for brain temperature during hyperthermia.

Main Methods:

  • Dogs were subjected to systemic hyperthermia using extracorporeal blood circulation.
  • Auditory brainstem response (ABR) was measured.
  • Brain temperature was monitored.

Main Results:

  • Increased brain temperature led to shortened ABR latency and reduced amplitude.

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  • Latency shortening was more pronounced in later waves (e.g., wave 4) compared to earlier waves (e.g., wave 1).
  • Observed changes suggest alterations in central nervous system conduction velocity.

    • Conclusions:

    • ABR latency is sensitive to changes in brain temperature.
    • ABR latency can serve as a clinically useful indicator of brain temperature during systemic hyperthermia.