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Updated: Feb 19, 2026

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
Published on: March 11, 2021
Benzene risk estimation using radiation equivalent coefficients
Aki Nakayama1, Tomomi Isono, Takuro Kikuchi
1Kyoto University, Graduate School of Engineering, Urban and Environmental Engineering, Kyoto Daigaku Katsura 4, Nishikyo, Kyoto, 615-8540, Japan. nakayama@risk.env.kyoto-u.ac.jp
Abstract:
We estimated benzene risk using a novel framework of risk assessment that employed the measurement of radiation dose equivalents to benzene metabolites and a PBPK model. The highest risks for 1 microg/m(3) and 3.2 mg/m(3) life time exposure of benzene estimated with a linear regression were 5.4 x 10(-7) and 1.3 x 10(-3), respectively. Even though these estimates were based on in vitro chromosome aberration test data, they were about one-sixth to one-fourteenth that from other studies and represent a fairly good estimate by using radiation equivalent coefficient as an "internal standard."
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