Evaluation of a powered intraosseous device for bone marrow sampling
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Updated: Jun 25, 2026

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
Published on: March 5, 2018
1Cancer Care Centers of South Texas, 2310 NE Loop 410, San Antonio, TX 78217, USA.
Background:
Our objective was to evaluate a powered bone marrow aspiration device for use in diagnosing disease and monitoring disease course and medical therapy.
Patients And Methods:
The device was used in accordance with practice guidelines and directions for use. Data collection included insertion success, time to insertion and complications. Patient pain levels were rated 0-10 (10 = extreme pain). Device operators rated ease of use of the device 0-10 (10 = outstanding).
Results:
There were 55 patients from three centers. Successful insertion and aspiration were achieved in 54 out of 55 patients (98.1%). Mean insertion time was 4.9 +/- 3.0 seconds; significantly faster than that previously reported. There were no complications. The mean insertion pain score was 2.5 +/- 2.2 and the mean aspiration pain score was 3.7 +/- 2.5. The six operators rated the ease of use of the device at a mean score of 8.3 +/- 1.7.
Conclusion:
Findings suggest that the powered aspiration device is safe and effective for bone marrow aspirations.

