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Updated: Jun 25, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Five cases of paralytic strabismus as a rare feature of lyme disease
Arnaud Sauer1, Yves Hansmann, Benoît Jaulhac
1Departments of Ophthalmology, Pole Specialty Medecine Ophthalmology Hygiene, Hopitaux Universitaires de Strasbourg, Strasbourg, France. arnaud.sauer@gmail.com
Abstract:
Lyme borreliosis is the most common human tick-borne disease in the Northern Hemisphere. The prevalence of Lyme borreliosis is estimated to be 20-100 cases per 100,000 persons in the United States and 100-155 cases per 100,000 persons in Europe [ 1 , 2 ]. It is caused by the spirochete Borrelia burgdorferi sensu lato [ 2 , 3 ]. The course of clinical manifestations is thought to occur in 3 stages: early, disseminated, and chronic [ 2 , 4 ]. Lyme borreliosis can cause a variety of ocular manifestations, and the frequency of these manifestations among cases of Lyme disease involving systemic manifestations is approximately 1% [ 5 ].
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