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Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

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Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
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Updated: Jun 25, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
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Published on: February 14, 2022

[Optimized negative pressure therapy. Case report].

G Drossard1, B Potier, M Steff

  • 1Service de chirurgie plastique reconstructrice et esthétique, CHU d'Angers, 4, rue Larrey, 49100 Angers, France. Dr.GuillaumeDrossard@mac.com

Annales De Chirurgie Plastique Et Esthetique
|February 6, 2009
PubMed
Summary
This summary is machine-generated.

This study presents a novel approach for abdominal wall reconstruction using Wisebands and negative pressure therapy (NPT) in a patient with severe skin necrosis. The combined treatment facilitated faster wound closure without flaps, resulting in a solid abdominal wall with no complications after 18 months.

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Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
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Last Updated: Jun 25, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
09:31

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism

Published on: February 14, 2022

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
09:41

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications

Published on: May 10, 2024

Area of Science:

  • Dermatology
  • Surgical Reconstruction
  • Oncology

Background:

  • A 53-year-old patient with a history of dermatomyositis and subcutaneous calcinosis presented with major abdominal cutaneous necrosis.
  • The patient had been on long-term treatment with immunosuppressants (Imurel) and high-dose corticosteroids, compromising their healing capacity.

Observation:

  • A large full-thickness abdominal wall defect was present after debridement.
  • Standard reconstructive options like local or pediculated flaps were deemed high-risk due to the patient's debilitated state.

Findings:

  • A combined approach using Wisebands for cutaneous extension and negative pressure therapy (NPT) for wound bed preparation was employed.
  • Optimized NPT was used for 2 weeks, followed by Wisebands for 1 month, with the entire treatment lasting 50 days and requiring five anesthesia sessions.
  • Histopathological analysis revealed an Epstein-Barr virus (EBV) lymphoma, which influenced treatment duration and hospitalization.

Implications:

  • The synergistic effect of Wisebands and NPT led to accelerated and successful skin closure of the abdominal defect.
  • This innovative technique provided a solid abdominal wall reconstruction without the need for flaps or separation, demonstrating a durable outcome 18 months post-treatment.
  • The findings suggest a promising alternative for complex abdominal wall reconstruction in high-risk patients.