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Updated: Jun 25, 2026

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
Published on: February 23, 2020
[Transcranial magnetic stimulation and cerebral physiology in psychiatric disorders]
1d.schutter@uu.nl
Background:
Transcranial magnetic stimulation (tms) is a technique that is being used increasingly to investigate the biological precursors of psychiatric disorders.
Aim:
To survey the current knowledge about deficits in local cerebral physiologic processes, as measured with tms methods in patients with obsessive-compulsive disorder, depression, schizophrenia or attention deficit/ hyperactivity disorder.
Method:
Aspects of cortical excitability and functional connectivity between the cerebral hemispheres as measured with single and paired-pulse tms were investigated by reviewing the scientific literature. results Obsessive compulsive disorder, depression, schizophrenia and attention deficit/ hyperactivity disorder are found to be associated with aberrant cerebral excitability and impaired functional connectivity.
Conclusion:
TMS is a suitable tool for examining unique aspects of brain physiology in individuals with a psychiatric condition.
