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Updated: Jun 25, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
[On-pump coronary artery bypass grafting is still useful for the complete revascularization of low risk patients]
F Oguma1, M Sugawara, H Hirahara
1Department of Cardiovascular Surgery, Japanese Red Cross Nagaoka Hospital, Nagaoka, Japan.
Insights
Complete arterial grafting in coronary artery bypass grafting (CABG) offers the best long-term results. Off-pump CABG is preferred for reduced mortality, but on-pump CABG may be suitable for select low-risk patients.
Area of Science:
- Cardiovascular Surgery
- Surgical Outcomes
- Grafting Techniques
Context:
- Complete revascularization using total arterial grafts is associated with superior late surgical outcomes in coronary artery bypass grafting (CABG).
- Off-pump CABG demonstrates advantages in morbidity and mortality compared to on-pump CABG (ONCABG).
- Challenges exist in achieving complete revascularization for multi-vessel disease using off-pump techniques, potentially necessitating cardiopulmonary bypass (CPB).
Purpose:
- To evaluate the optimal surgical strategy for coronary revascularization, balancing completeness of revascularization with the risks associated with cardiopulmonary bypass.
- To identify patient subgroups who may benefit from either on-pump or off-pump CABG, considering surgical complexity and patient risk factors.
Summary:
- Complete arterial grafting yields the best long-term surgical results in CABG.
- While off-pump CABG is generally superior, on-pump CABG may be considered for low-risk patients requiring extensive posterior wall revascularization.
- Acute conversion from off-pump to on-pump procedures increases complication rates and mortality, underscoring the importance of pre-operative planning.
Impact:
- This analysis aids surgeons in selecting the most appropriate CABG strategy, potentially improving patient outcomes and reducing perioperative complications.
- Highlights the trade-offs between complete revascularization and the risks of cardiopulmonary bypass in different patient populations.
- Informs clinical decision-making regarding the use of on-pump versus off-pump CABG for complex coronary artery disease.
Abstract:
Many clinical studies demonstrate that complete revascularization with total arterial grafts leads to the best late surgical results. Though off-pump coronary artery bypass grafting (CABG) is superior to on-pump CABG (ONCABG) in morbidity and mortality, some coronary surgeons feel it difficult to revascularise multi-vessel disease completely without cardiopulmonary bypass (CPB). Acute conversion from off-pump to on-pump results in increased major complications and high mortality. For the patients with high risk for CPB, coronary revascularization should be performed without CPB even if completeness is failed. It seems to be reasonable to adopt ONCABG for low risk patients who need many anastomoses in the posterior wall of the heart.
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