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Updated: Jun 25, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Acute stroke intervention by interventional cardiologists
James T DeVries1, Christopher J White, Tyrone J Collins
1Department of Cardiovascular Diseases, The Ochsner Heart and Vascular Institute, Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA.
Insights
Catheter-based therapy (CBT) is a safe and effective treatment for acute ischemic stroke in patients ineligible for intravenous thrombolysis. This study shows successful recanalization and improved outcomes with CBT in this patient population.
Area of Science:
- Neurology
- Interventional Cardiology
- Vascular Medicine
Background:
- Acute ischemic stroke is a prevalent condition often undertreated.
- Catheter-based therapy (CBT) presents a viable treatment option for select patients unsuitable for intravenous thrombolysis.
Purpose of the Study:
- To evaluate the technical success and clinical outcomes of CBT for acute ischemic stroke.
- To assess CBT in patients who do not qualify for intravenous thrombolysis.
Main Methods:
- Retrospective review of consecutive stroke patients undergoing CBT.
- Data collection included demographics, NIHSS, procedural details, and in-hospital/90-day outcomes.
- Interventional cardiologists provided CBT with stroke neurologist support.
Main Results:
- Successful recanalization was achieved in 88% of 26 CBT-treated patients.
- In-hospital adverse events occurred in 15%, with intracerebral hemorrhage in 12%.
- National Institutes of Health Stroke Scale scores improved significantly (16.5 to 9.9; P < 0.001), with 50% achieving a modified Rankin score ≤2.
Conclusions:
- CBT is a safe and effective treatment for acute stroke patients ineligible for intravenous thrombolysis.
- Qualified interventional cardiologists and stroke neurologists can successfully administer CBT.
Objectives:
To report the technical success and clinical outcomes of catheter-based therapy (CBT) for acute ischemic stroke in patients ineligible for intravenous thrombolysis.
Background:
Acute ischemic stroke is common but undertreated. CBT for acute ischemic stroke is a therapeutic option in selected patients who are not candidates for intravenous thrombolysis.
Methods:
Consecutive stroke patients who were ineligible for intravenous thrombolysis and underwent CBT were identified by retrospective chart review. Demographic information, National Institutes of Health Stroke Scale (NIHSS), procedural characteristics, and clinical outcomes during hospitalization and at 90 days follow up were collected. Experienced interventional cardiologists with the consultative support of stroke neurologists were on call for acute strokes.
Results:
A total of 33 acute ischemic stroke patients underwent emergency cerebral angiography, with 26 patients undergoing CBT. Successful "culprit" artery recanalization was achieved in 23 (88%) of the 26 patients. In-hospital adverse events occurred in 4 (15%) patients, with intracerebral hemorrhage (ICH) (12%) representing the most common adverse event. The baseline NIHSS for patients who underwent intervention was 16.5 +/- 9.9 (median 16) and improved significantly to 9.9 +/- 8.7 (median 9) (P < 0.001) at hospital discharge. A modified Rankin score of two or less (indicating mild disability) was achieved in half (n = 13) of the CBT treated patients. All cause mortality at 90 days was 8% (2/26).
Conclusions:
In selected patients, CBT provided by qualified interventional cardiologists supported by stroke neurologists, offers a safe and effective option for patients with acute stroke who are not eligible for intravenous thrombolysis.
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