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Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
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Diffusion01:12

Diffusion

Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

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Related Experiment Video

Updated: Jun 25, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

[Diffusion tensor imaging].

Harushi Mori1

  • 1Department of Radiology, University of Tokyo Hospital.

Rinsho Shinkeigaku = Clinical Neurology
|February 10, 2009
PubMed
Summary

Diffusion tensor imaging (DTI) and tractography visualize white matter pathways for surgical planning and disease detection. This advanced MRI technique offers sensitive quantitative measurements for neurological and psychiatric conditions.

Area of Science:

  • Neuroimaging
  • Neuroscience
  • Radiology

Context:

  • Diffusion tensor imaging (DTI) and diffusion tensor tractography are advanced magnetic resonance imaging techniques.
  • These methods allow for in vivo visualization and quantitative evaluation of white matter pathways.

Purpose:

  • To highlight the utility of DTI and tractography in neuroscience and clinical practice.
  • To demonstrate the application of DTI in visualizing white matter tracts in relation to brain lesions.
  • To emphasize the role of quantitative tract measurements in detecting neurodegenerative and psychiatric diseases.

Summary:

  • DTI and tractography provide unique in vivo visualization and segmentation of white matter pathways.
  • Three-dimensional fiber visualization, including corticospinal tracts, aids in stereotactic radiosurgery, preoperative evaluation, and intraoperative navigation.

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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
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DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions
10:05

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

Published on: August 26, 2014

  • Quantitative tract analysis is highly sensitive for detecting subtle differences in patients with neurodegenerative, neurocognitive, and psychiatric disorders like ALS, schizophrenia, and Alzheimer's disease.

    • Impact:

    • This technology is crucial for precise surgical planning and navigation in neurosurgery.
    • DTI offers a sensitive tool for early detection and monitoring of white matter changes in various neurological and psychiatric conditions.
    • The future clinical and neuroscience applications of DTI are expected to expand significantly.