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Related Experiment Video

Updated: Jun 25, 2026

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets
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Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

Published on: March 17, 2023

On-chip surface plasmon resonance sensor.

Hyungseok Pang1, Hyoung J Cho, Patrick L Likamwa

  • 1College of Optics and Photonics: CREOL and FPCE, University of Central Florida, Orlando, Florida, 32816, USA.

Journal of Nanoscience and Nanotechnology
|February 10, 2009
PubMed
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A new on-chip micro surface plasmon resonance (SPR) sensor was developed on an optoelectronic platform. This miniaturized, high-throughput sensor shows potential for advanced biosensing applications.

Area of Science:

  • Optoelectronics
  • Nanotechnology
  • Biosensing

Background:

  • Surface Plasmon Resonance (SPR) is a powerful label-free optical sensing technique.
  • Current SPR systems can be bulky and lack integration, limiting high-throughput applications.
  • Developing miniaturized and integrated SPR sensors is crucial for point-of-care diagnostics and advanced research.

Purpose of the Study:

  • To develop a novel on-chip micro SPR sensor.
  • To create a fully integrated SPR sensor system for miniaturization and high throughput.
  • To investigate a new method for the design and fabrication of solid-state SPR sensor devices.

Main Methods:

  • Development of an optoelectronic platform for the SPR sensor.
  • Design and fabrication of a novel solid-state SPR sensor device.

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Last Updated: Jun 25, 2026

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets
06:12

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

Published on: March 17, 2023

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions
09:09

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions

Published on: November 23, 2015

  • Proof-of-concept demonstration using a simulated binding experiment to generate and detect SPR signals.

    • Main Results:

    • Successful development of a novel on-chip micro SPR sensor.
    • Demonstration of signal generation and detection from the proposed optoelectronic platform.
    • Validation of the fabricated solid-state SPR sensor device through simulated binding.

    Conclusions:

    • The developed on-chip micro SPR sensor represents a significant advancement in integrated sensing technology.
    • The optoelectronic platform enables a miniaturized and high-throughput SPR sensing system.
    • This novel sensor design and fabrication method pave the way for future high-performance biosensing applications.