Related Experiment Video
Updated: Jun 25, 2026

Quantification of Violacein in Chromobacterium violaceum and Its Inhibition by Bioactive Compounds
Published on: August 8, 2025
Velleratretraol, an unusual highly functionalized lactarane sesquiterpene from Lactarius vellereus
Du-Qiang Luo1, Li-Yan Zhao, Yao-Long Shi
1College of Life Science, Key Laboratory of Pharmaceutical Chemistry and Molecular Diagnosis, Ministry of Education and Research Center of Biotechnology of Hebei Province, Hebei University, Baoding, China. duqiangluo@163.com
Abstract:
An unusual highly functionalized lactarane sesquiterpene, named velleratretraol (1), was isolated from the ethanol extract of the fruiting body of the mushroom Lactarius vellereus. Its structure was determined through spectroscopic analysis and single-crystal X-ray diffraction studies. The proposed assignment of the absolute configuration is based on computational results. It showed weak activity against HIV-1 cells with an effective concentration of 68.0 microg ml(-1) and a selectivity index of 2.0.
Related Concept Videos
Inhibitors of Gram-positive Cell Wall Synthesis
Alkylation of β-Diester Enolates: Malonic Ester Synthesis
Lysosomal Hydrolases
Reactions of Aldehydes and Ketones: Baeyer–Villiger Oxidation
The carbonyl center is activated by...
Loss of Carboxy Group as CO2: Decarboxylation of Malonic Acid Derivatives
Transducer Mechanism: Enzyme-Linked Receptors
Major types that are helpful drug targets include:
