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Updated: Jun 25, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
Published on: April 11, 2016
[Molecular pathology as an necessity: its role in diagnostic and predictive pathology]
1Institut für Pathologie und Neuropathologie, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Deutschland. kw.schmid@uk-essen.de
Abstract:
Individualized therapeutic regimes are almost exclusively based on the rapid developments in molecular pathology. Application of (additional) molecular pathological investigations may thus offer the unique opportunity to improve the classical morphologic diagnosis as well as to routinely evaluate the parameters ("biomarkers") required for therapeutic decision making. Pathologists are thus facing the cogent necessity to perform and develop molecular pathological investigations in high quality and to establish biobanks, as well as to adjust their specialist training accordingly in order to meet these requirements.
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