Related Experiment Video
Updated: Jun 25, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Nursing home-acquired pneumonia
1Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215-1199, USA. solh@buffalo.edu
Abstract:
Nursing home-acquired pneumonia (NHAP) was first described in 1978. Since then there has been much written regarding NHAP and its management despite the lack of well-designed studies in this patient population. The most characteristic features of patients with NHAP are the atypical presentation, which may lead to delay in diagnosis and therapy. The microbial etiology of pneumonia encompasses a wide spectrum that spans microbes recovered from patients with community-acquired pneumonia to organisms considered specific only to nosocomial settings. Decision to transfer a nursing home patient to an acute care facility depends on a host of factors, which include the level of staffing available at the nursing home, patients' advance directives, and complexity of treatment. The presence of risk factors for multidrug-resistant pathogens dictates approach to therapy. Prevention remains the cornerstone of reducing the incidence of disease. Despite the advance in medical services, mortality from NHAP remains high.
Insights
Nursing home-acquired pneumonia (NHAP) presents atypically, delaying diagnosis and treatment. Despite advances, NHAP mortality remains high, emphasizing the need for prevention strategies.
Area of Science:
- Geriatric Medicine
- Infectious Diseases
- Pulmonology
Background:
- Nursing home-acquired pneumonia (NHAP) was first described in 1978.
- Management strategies exist, but well-designed studies are lacking.
- NHAP patients often present atypically, delaying diagnosis and treatment.
Purpose of the Study:
- To review the characteristics, challenges, and management of NHAP.
- To highlight the importance of prevention in NHAP.
Main Methods:
- Literature review of NHAP studies.
- Analysis of diagnostic and therapeutic challenges.
- Discussion of risk factors and prevention.
Main Results:
- NHAP etiology spans community- and hospital-acquired pathogens.
- Transfer decisions involve staffing, directives, and treatment complexity.
- Risk factors for multidrug-resistant pathogens influence therapy.
Conclusions:
- NHAP requires careful consideration due to atypical presentations and high mortality.
- Prevention is crucial for reducing NHAP incidence.
- Despite medical advances, NHAP remains a significant clinical challenge.
Related Concept Videos
Pneumonia I: Introduction
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Pneumonia III: Complications and Assessment
Atypical Pneumonia
Pneumonia II: Pathophysiology
