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A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
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Published on: February 16, 2020

Catalytic formal Homo-Nazarov cyclization.

Filippo De Simone1, Julien Andrès, Riccardo Torosantucci

  • 1Laboratory of Catalysis and Organic Synthesis Ecole Polytechnique Fédérale de Lausanne EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne, Switzerland.

Organic Letters
|February 10, 2009
PubMed
Summary

Researchers developed the first catalytic method for vinyl-cyclopropyl ketone cyclization, a formal homo-Nazarov reaction. This new approach efficiently synthesizes heterocyclic and carbocyclic compounds from activated cyclopropanes under mild conditions.

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