Related Experiment Video
Updated: Jun 25, 2026

Semi-Automatic Graphical Tool for Measuring Coronary Artery Spatially Weighted Calcium Score from Gated Cardiac Computed Tomography Images
Published on: September 22, 2023
Practical tips and tricks in cardiovascular computed tomography: non-contrast "heartscans"--beyond the calcium score
1The Princeton Longevity Center, Princeton Forrestal Village, 136 Main Street, Princeton, NJ 08540, USA. jrumberger@theplc.net
Insights
The heartscan provides valuable coronary artery calcium (CAC) scoring for cardiovascular risk assessment. Emerging research reveals additional prognostic information beyond CAC scores from heart scans.
Area of Science:
- Cardiovascular Imaging and Risk Stratification
- Preventive Cardiology
- Medical Diagnostics
Background:
- Coronary artery calcium (CAC) scoring via non-contrast CT heart scans is established for cardiovascular risk assessment.
- Hundreds of studies confirm CAC score's independent value beyond traditional risk factors.
- Recent findings suggest heart scans offer more prognostic data than previously recognized.
Purpose of the Study:
- To explore additional information obtainable from heart scans beyond the Agatston CAC score.
- To highlight emerging applications of heart scan data in risk stratification.
- To review novel insights derived from cardiac CT imaging.
Main Methods:
- Analysis of existing literature and recent data on cardiac CT "heartscan" utility.
- Review of studies evaluating CAC score applicability across diverse populations.
- Examination of data on non-calcium related findings from cardiac CT.
Main Results:
- Heart scans provide data beyond total CAC score, including applicability across ethnic groups and prognostication in the elderly.
- Concept of "heart age" versus chronological age aids individual risk stratification.
- Evaluation of CAC distribution, left ventricular size, aortic dimensions, and epicardial fat offers further prognostic insights.
Conclusions:
- Cardiac CT "heartscans" offer comprehensive cardiovascular risk assessment beyond the Agatston CAC score.
- Utilizing all available data from heart scans enhances personalized risk prediction.
- Further research into novel metrics from cardiac CT is warranted for improved patient outcomes.
Abstract:
The Agatston total coronary artery calcium (CAC) score, derived from a non-contrast CT scan of the heart (also known as the "heartscan") in asymptomatic and symptomatic patients, has been shown to provide incremental and independent assessment to conventional risk factors based upon literally hundreds of studies published from around the world. However, recent data have emerged to indicate that there is additional information which can be derived from a "heartscan" beyond the calcium score. These include recent data on the applicability across ethnic sub-groups, prognostication in the elderly, defining "heart age" versus chronological age for individual risk stratification, evaluating CAC distribution in addition to total CAC score, and looking beyond the coronary arteries regarding left ventricular size, aortic root/thoracic aorta diameter, and epicardial fat.
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies for Cardiovascular System IV: CMRI
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...

