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Updated: Jun 25, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Three-dimensional echocardiographic assessment of acquired left ventricular to right atrial shunt (Gerbode defect)
Kibar Yared1, Jorge Solis, Jonathan Passeri
1Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA. kyared@partners.org
Insights
A novel acquired Gerbode defect was identified after aortic valve replacement. Real-time 3-dimensional echocardiography accurately visualized the left-to-right shunt, aiding in treatment planning.
Area of Science:
- Cardiology
- Medical Imaging
- Cardiac Surgery
Background:
- Bioprosthetic aortic valve replacement can be complicated by recurrent endocarditis.
- Acquired Gerbode defects, a rare complication, involve shunting between the left ventricle and right atrium.
Observation:
- A 60-year-old male presented with recurrent endocarditis post-aortic valve replacement.
- Transthoracic echocardiography revealed a left-to-right shunt from the left ventricular outflow tract to the right atrium, consistent with an acquired Gerbode defect.
Findings:
- Real-time 3-dimensional echocardiography precisely delineated the shunt's origin and trajectory.
- Accurate differentiation from tricuspid regurgitation is crucial for avoiding overestimated right ventricular systolic pressure.
Implications:
- 3D echocardiography offers detailed visualization of acquired Gerbode defects.
- This imaging modality aids in planning optimal surgical or catheter-based interventions for complex cardiac defects.
Abstract:
A 60-year-old man was readmitted 1 year after bioprosthetic aortic valve replacement for recurrent endocarditis. Transthoracic 2-dimensional color Doppler revealed a novel finding of a left-to-right shunt from the left ventricular outflow tract to the right atrium immediately superior to the septal leaflet of the tricuspid valve consistent with an acquired Gerbode defect. Real-time 3-dimensional echocardiography was used to accurately delineate the course of the shunt. To avoid overestimating right ventricular systolic pressure by mistaking such a shunt for an eccentric jet of tricuspid regurgitation, it is important to accurately differentiate the two. Real-time 3-dimensional echocardiography now provides rapid, detailed 3-dimensional appreciation of the origin and course of such shunts with easy facility of orienting views to the flows of interest by cropping. Such information can help design optimal surgical or catheter-based therapy.
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