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Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis

E A M Festen1, P Goyette, R Scott

  • 1Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Gut
|February 10, 2009
PubMed
Summary

The IL2/IL21 genetic locus is strongly associated with ulcerative colitis (UC) and moderately with Crohn's disease (CD). This finding confirms the IL2/IL21 region as a susceptibility locus for inflammatory bowel diseases (IBDs).

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