Related Experiment Video
Updated: Jun 25, 2026

09:15
Inducing and Characterizing Vesicular Steatosis in Differentiated HepaRG Cells
Published on: July 18, 2019
The sulfated polysaccharide porphyran reduces apolipoprotein B100 secretion and lipid synthesis in HepG2 cells
Nao Inoue1, Naomi Yamano, Kotaro Sakata
1Department of Applied Biochemistry and Food Science, Saga University, Japan.
Bioscience, Biotechnology, and Biochemistry
|February 10, 2009
Abstract:
The physiological effect of porphyran, a sulfated polysaccharides from an edible red alga, was studied in human hepatoma HepG2 cells. Porphyran supplementation significantly decreased apolipoprotein B100 secretion, and the reduction was partly associated with suppression of cellular lipid synthesis in HepG2 cells. This is the first study to elucidate the mechanism of the hypolipidemic effect of porphyran.

