Related Experiment Video
Updated: Jun 25, 2026

Multi-Gene Single Nucleotide Polymorphism Detection in Gastric Cancer Based on Ion Semiconductor Sequencing Platform
Published on: May 10, 2024
Effects of UVA irradiation on the concentration of folate in human blood
Tsutomu Fukuwatari1, Mio Fujita, Katsumi Shibata
1Department of Food Science and Nutrition, School of Human Cultures, The University of Shiga Prefecture, Hikone, Shiga, Japan. fukkie@shc.usp.ac.jp
Abstract:
Although it is well known that ultraviolet A (UVA) irradiation destroys folate, no definite conclusion for the biological degradation has yet been drawn. In the present study, we determined the effects of UVA exposure on the blood folate concentration in vitro and in vivo. UVA irradiation reduced the synthesized folate pteroylmonoglutamic acid (PGA) content in the blood, but not 5-methyltetrahydrofolate, a major folate form in the blood stream. Exposure to sunlight also decreased the plasma folate concentration in human subjects who took PGA prior to the exposure, but not in subjects who did not take PGA. These results suggest that UVA exposure destroyed PGA but not 5-methyltetrahydrofolate in human blood in vivo.
Related Concept Videos
Mutations
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

