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Gastrointestinal complications in critically ill patients: what differs between adults and children?
1Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain. pielvi@ya.com
Insights
Gastrointestinal complications in critically ill patients are common and vary widely due to differing diagnostic criteria. Key risk factors include shock and certain medications, impacting enteral nutrition efficacy.
Area of Science:
- Critical Care Medicine
- Gastroenterology
- Pediatrics
Background:
- Gastrointestinal complications are a significant concern in critically ill patients.
- Variability in incidence and severity exists between pediatric and adult populations.
- Enteral nutrition is crucial but can be hindered by these complications.
Purpose of the Study:
- To analyze and compare causes, incidence, severity, and treatment of gastrointestinal complications in critically ill children and adults.
- To review current literature on gastrointestinal issues in intensive care settings.
- To identify risk factors and underlying mechanisms of these complications.
Main Methods:
- Literature review and comparative analysis of existing studies.
- Examination of incidence, causes, severity, and treatment strategies.
- Focus on critically ill pediatric and adult populations.
Main Results:
- Incidence data is highly variable due to lack of unified diagnostic criteria.
- Gastrointestinal complications related to nutrition appear less frequent in children than adults.
- Shock and drug administration (catecholamines, sedatives, muscle relaxants) are primary risk factors; altered motility underlies issues like gastric residue and constipation.
Conclusions:
- Gastrointestinal complications impede enteral nutrition, potentially increasing morbidity and mortality.
- Consensus on diagnostic criteria for gastric residues, constipation, and diarrhea is needed.
- Further research should evaluate prokinetic agents, dietary interventions, and laxatives for managing motility disorders and constipation in critically ill patients.
Purpose Of Review:
The objective of this review has been to analyse and compare the causes, incidence, severity and treatment of gastrointestinal complications in critically ill children and adults.
Recent Findings:
The incidence of gastrointestinal complications in critically ill patients published in the literature is very variable owing to the absence of unified diagnostic criteria both in children and adults. The incidence of gastrointestinal complications related to nutrition appears to be lower in children than in adults, and there are no differences in the incidence of gastrointestinal complications between gastric and transpyloric nutrition except with respect to the volume of gastric residues. The most important risk factors for digestive tract complications are shock and the administration of drugs (catecholamines, sedatives and muscle relaxants). Altered gastrointestinal motility is the principal mechanism underlying an excessive gastric residue, abdominal distension and constipation.
Summary:
Gastrointestinal complications limit the efficacy of enteral nutrition in the critically ill patient and can affect morbidity and mortality. Consensus must be reached on the definition of the criteria of excessive gastric residues, constipation and diarrhoea, and studies must be performed that evaluate the efficacy of prokinetic agents on altered gastrointestinal motility and the effects of diet and laxatives on constipation in the critically ill adult and child.
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