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Standard reference materials for analysis of dietary supplements.

Katherine E Sharpless¹, David L Duewer

¹National Institute of Standards and Technology, Analytical Chemistry Division, 100 Bureau Dr, Stop 8390, Gaithersburg, MD 20899-8390, USA. katherine.sharpless@nist.gov

Journal of AOAC International

|February 11, 2009

Summary

The National Institute of Standards and Technology is developing Standard Reference Materials (SRMs) for dietary supplements. These materials are crucial for ensuring the accuracy and reliability of supplement testing and quality control.

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Area of Science:

Analytical Chemistry
Materials Science
Food and Nutrition Science

Background:

Dietary supplements require rigorous quality control to ensure safety and efficacy.
Accurate analytical methods are essential for assessing the composition of dietary supplements.
Standard Reference Materials (SRMs) provide a critical benchmark for analytical measurements.

Purpose of the Study:

To announce the development of new Standard Reference Materials (SRMs) for dietary supplements.
To highlight the importance of SRMs in the quality control of natural-matrix products.
To promote the use of SRMs for method validation and traceability in dietary supplement analysis.

Main Methods:

Collaboration between government agencies including the National Institute of Standards and Technology (NIST), National Institutes of Health-Office of Dietary Supplements (NIH-ODS), and U.S. Food and Drug Administration (FDA).

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Production of certified Standard Reference Materials (SRMs) specifically for dietary supplements.

Focus on natural-matrix SRMs to reflect real-world sample complexity.

Main Results:

SRMs for dietary supplements are being produced.
These SRMs are suitable for various analytical applications.
Traceability of measurements can be established using these SRMs.

Conclusions:

The availability of NIST-produced SRMs for dietary supplements will enhance analytical accuracy.
These SRMs are vital tools for method validation and quality control in the dietary supplement industry.
Utilizing SRMs will improve the overall reliability and safety of dietary supplements through established traceability.