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Obesity

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...

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Updated: Jun 25, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

[Concept and classification of obesity].

Kiminori Hosoda¹, Midori Ida, Masakazu Hirata

¹Department of Endocrinology and Metabolism, Kyoto University Graduate School of Medicine.

Nihon Rinsho. Japanese Journal of Clinical Medicine

|February 11, 2009

Summary

Obesity is a global disease linked to health issues like hypertension and diabetes. This review explores obesity and metabolic syndrome, focusing on adipotoxicity as a key factor.

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Assessment of Child Anthropometry in a Large Epidemiologic Study

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Published on: February 2, 2017

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Localization, Identification, and Excision of Murine Adipose Depots

Localization, Identification, and Excision of Murine Adipose Depots

Published on: December 4, 2014

Area of Science:

Endocrinology
Metabolic Diseases
Public Health

Background:

Obesity is defined as a disease when accompanied by current or future health complications.
Metabolic syndrome, characterized by obesity, hypertension, glucose intolerance, and lipid disorders, increases arteriosclerotic disease risk.
The global prevalence of obesity underscores its significance as a pandemic health concern.

Purpose of the Study:

To explain the concept and classification of obesity.
To discuss the underlying disease mechanisms of obesity and metabolic syndrome.
To highlight the role of adipotoxicity in obesity and metabolic syndrome.

Main Methods:

Review of existing literature on obesity and metabolic syndrome.
Analysis of the pathophysiological basis of obesity.
Examination of adipotoxicity as a central mechanism.

Main Results:

Obesity is a complex disease with various classifications.
Metabolic syndrome is a cluster of conditions associated with increased cardiovascular risk.
Adipotoxicity, or the toxic effects of excess adipose tissue, is a critical factor in metabolic dysfunction.

Conclusions:

Understanding obesity and metabolic syndrome is crucial for public health.
Adipotoxicity provides a key perspective for comprehending the disease basis of these conditions.
Further research into adipotoxicity may lead to novel therapeutic strategies.