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Updated: Jun 25, 2026

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

Published on: September 27, 2024

[Metabolic syndrome].

Masanori Mitsuishi¹, Kazutoshi Miyashita, Hiroshi Itoh

¹Department of Internal Medicine, School of Medicine, Keio University.

Nihon Rinsho. Japanese Journal of Clinical Medicine

|February 11, 2009

Summary

Visceral obesity significantly contributes to metabolic syndrome, a cluster of conditions increasing cardiovascular disease risk. Treatments targeting obesity can positively impact metabolic syndrome components.

Area of Science:

Metabolic health
Obesity research
Cardiovascular disease prevention

Background:

Metabolic syndrome, characterized by hypertension, dyslipidemia, and impaired glucose tolerance, is a major risk factor for cardiovascular diseases.
Obesity, particularly visceral obesity, is a key upstream factor in the pathogenesis of metabolic syndrome.
Emerging research links obesity to metabolic syndrome through inflammation, adipokine dysregulation, and mitochondrial dysfunction.

Purpose of the Study:

To review the intricate relationship between obesity and metabolic syndrome.
To elucidate the specific role of visceral obesity in metabolic syndrome development.
To explore how obesity treatments influence metabolic syndrome.

Main Methods:

Literature review of recent studies on obesity and metabolic syndrome.

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Published on: January 19, 2017

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Last Updated: Jun 25, 2026

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

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Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

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Published on: January 19, 2017

Analysis of mechanistic pathways connecting obesity to metabolic syndrome.

Synthesis of evidence on the impact of obesity interventions on metabolic syndrome.

Main Results:

Visceral obesity is a critical driver of metabolic syndrome.
Inflammation, adipokine imbalance, and mitochondrial dysfunction are key mediating mechanisms.
Obesity treatments show potential for improving metabolic syndrome parameters.

Conclusions:

Understanding the obesity-metabolic syndrome link is crucial for cardiovascular health.
Targeting visceral fat offers a promising therapeutic strategy for metabolic syndrome.
Effective obesity management is vital for mitigating metabolic syndrome and its complications.