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Related Experiment Video

Updated: Jun 25, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Current indications for post-mastectomy radiation.

Maria Vilarino-Varela1, Yaw Sinn Chin, Andreas Makris

  • 1Academic Oncology Unit, Mount Vernon Cancer Centre, Rickmansworth Road, Northwood, Middlesex, HA6 2RN, UK. amakris@nhs.net.

International Seminars in Surgical Oncology : ISSO
|February 11, 2009
PubMed
Summary
This summary is machine-generated.

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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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Post-mastectomy radiotherapy is proven to reduce locoregional failure and now shows a survival benefit. This review outlines the current indications for this important breast cancer treatment.

Area of Science:

  • Oncology
  • Radiotherapy
  • Breast Cancer Management

Background:

  • Post-mastectomy radiotherapy (PMRT) is a standard treatment following mastectomy for breast cancer.
  • Historically, PMRT was known to decrease locoregional recurrence rates.
  • Recent evidence has established a significant survival advantage associated with PMRT.

Purpose of the Study:

  • To review and synthesize the current clinical indications for PMRT.
  • To provide an updated overview of evidence supporting PMRT use.
  • To guide clinical decision-making regarding PMRT in breast cancer patients.

Main Methods:

  • Literature review of relevant studies on post-mastectomy radiotherapy.
  • Synthesis of evidence regarding efficacy and survival outcomes.

Related Experiment Videos

Last Updated: Jun 25, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

  • Analysis of current guidelines and clinical trial data.

    • Main Results:

    • PMRT significantly reduces the risk of locoregional failure after mastectomy.
    • A survival benefit has been demonstrated in multiple studies.
    • Specific patient subgroups and risk factors are identified for PMRT indication.

    Conclusions:

    • PMRT is indicated for patients with high-risk features after mastectomy.
    • The survival benefit reinforces the importance of appropriate PMRT use.
    • Current indications focus on optimizing PMRT delivery for improved patient outcomes.