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Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
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Anesthetic management for instrumentation of the pregnant rhesus monkey

E A Sanders1, R D Gleed, P W Nathanielsz

  • 1Department of Physiology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.

Journal of Medical Primatology
|July 1, 1991
PubMed

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.