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Related Experiment Video

Updated: Jun 25, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

Does risperidone improve hyperacusia in children with autism?

Ahmad Ghanizadeh¹

¹Shiraz University of Medical Sciences, Hafez Hospital, Shiraz, Iran. ghanizad@sina.tums.ac.ir

Psychopharmacology Bulletin

|February 11, 2009

Summary

This case study suggests risperidone may improve hyperacusis (sound sensitivity) in children with autism. Symptoms improved with the medication and returned upon discontinuation, indicating a potential therapeutic effect.

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Area of Science:

Neurodevelopmental Disorders
Pharmacology
Auditory Processing

Background:

Autism Spectrum Disorder (ASD) is often associated with sensory processing differences, including hyperacusis (abnormal sound sensitivity).
Hyperacusis in children with autism can lead to significant distress and avoidance behaviors.
Limited research exists on pharmacological interventions for hyperacusis in this population.

Observation:

A 5.5-year-old girl diagnosed with autism and hyperacusis was treated with risperidone.
Maternal reports indicated a notable improvement in the severity of hyperacusis following risperidone initiation.

Findings:

Hyperacusis symptoms demonstrably improved after starting risperidone.
Discontinuation of risperidone led to the reappearance of hyperacusis.
A re-challenge with risperidone resulted in symptom improvement, supporting its potential efficacy.

Implications:

This case report suggests risperidone may be a potential treatment for hyperacusis in children with autism.
Further research is warranted to confirm these findings and explore the underlying mechanisms.
This study highlights the need for investigating targeted interventions for sensory symptoms in ASD.